Sarcopenia is a condition characterized by the progressive and generalized loss of skeletal muscle mass and function.
It primarily affects older individuals but can also occur in younger adults. Sarcopenia is associated with adverse outcomes such as disability, metabolic dysfunction, poor quality of life, and even increased mortality.
The condition can be caused by factors such as aging, sedentary lifestyle, malnutrition, immobilization, diabetes, obesity, and various inflammatory diseases.
Diagnosis of sarcopenia involves assessing parameters such as muscle mass, muscle strength, muscle performance, and walking speed. Different consensus papers have provided definitions and diagnostic criteria for sarcopenia, which generally revolve around low muscle mass combined with low muscle strength or low muscle performance.
While the exact causes of sarcopenia are not always clear, it can be categorized as primary or secondary. Primary sarcopenia occurs when the aging process itself is the main cause, whereas secondary sarcopenia is associated with other factors such as inactivity, inadequate nutrition, gastrointestinal disorders, certain medications, and diseases that affect muscle mass and overall health.